Correlation between the degree and stage of malignancy with environmental factors based on gender and age of patients in colorectal cancer patients

Introduction: Colorectal cancer is the third most common cancer in Iran. Some studies have shown that age and sex are associated with the course and prognosis of colorectal cancer. Due to the fact that recognizing the factors affecting colorectal cancer improves the screening system and selects better treatment modalities, and due to the lack of such studies in Iran, in this study, the relationship between the degree and stage of malignancy with environmental factors, gender and age of patients was examined for colorectal cancer. Materials and Methods: This is a descriptive cross-sectional study and the pathology report of samples of patients with colorectal cancer admitted during 1393-1397 in Poursina Hospital in Rasht (Iran) in terms of age, sex, tumor location and pathological stage of patients undergoing was evaluated. Results: From 94 pathology reports, the number of men was more than women and the highest number of patients were reported in the age group of 50-60 years. Abdominal pain was the most common clinical symptom at diagnosis. Most tumors were located in the rectum. Stage III had the highest frequency. Higher stages were statistically significantly associated with being a woman. There was no significant relationship between age and smoking and alcohol consumption with colorectal tumor stage. Also, the degree of tumor was not related to age and sex and history of smoking and alcohol consumption of patients. Conclusion: In this study, a significant relationship was found between the female gender and the higher stages of cancer. But there was no association between age and sex and smoking and alcohol consumption with the degree of cancer. Also, no relationship was found between age and smoking and alcohol consumption with the stage of cancer.